One Health studies that adopt a formal modelling approach: A scoping review.

While the One Health perspective provides a useful approach by which to influence the complex interactions that pose a risk to the individual and collective health of humans, animals, and the environment, approaches to its operationalization can be enhanced. This study examines models as contributors toward operationalization of One Health. It describes how modelling approaches have been applied to resolve the complexity of One Health problems. A scoping literature review is based on the PRISMA-Scr approach. The literature is mapped from a One Health (area of application) as well as from a modelling (model type, modelling trends, unit of analysis, level of abstraction) perspective. 24 articles were identified that address a spectrum from strategic to tactical and operational considerations in One Health, with the bulk of the work slanted towards the former two aspects. Models focus on supporting high-level decision-makers on disease management strategies, investments, and resource allocation, and were developed with involvement of a broad set of stakeholders in One Health. Evidence could be found of the use of the major categories of simulation models, namely, systems dynamic models, agent-based models, and discrete-event models. The identified models are used to address different levels of complexity and decision-making, as such pointing towards the potential for integrating different modelling approaches in informing One Health decision-making in practical contexts. • One Health provides a lens on the complexity of integrated health problems. • Modelling approaches provide a means of structuring One Health complexities. • A scoping review of modelling approaches in the One Health domain was undertaken. • Current approaches mostly support strategic and tactical decision-making. • Scope exists for integrated modelling frameworks to support One Health operationalisation. [ABSTRACT FROM AUTHOR]