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Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Inhibitors of CDK8 for the Treatment of Cancer.

Authors :
Li, Yangguang
Liu, Yingtao
Wu, Jianping
Liu, Xiaosong
Wang, Lin
Wang, Ju
Yu, Jiaojiao
Qi, Hongyun
Qin, Luoheng
Ding, Xiao
Ren, Feng
Zhavoronkov, Alex
Source :
Journal of Medicinal Chemistry; 4/27/2023, Vol. 66 Issue 8, p5439-5452, 14p
Publication Year :
2023

Details

Language :
English
ISSN :
00222623
Volume :
66
Issue :
8
Database :
Supplemental Index
Journal :
Journal of Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
163418890
Full Text :
https://doi.org/10.1021/acs.jmedchem.2c01718