Findings on Lupus Reported by Investigators at Kyushu University (Activation of Caspase-1 Is Mediated By Stimulation of Interferon Genes and Nlr Family Pyrin Domain Containing 3 In Monocytes of Active Systemic Lupus Erythematosus).

Keywords: Fukuoka; Japan; Asia; Apoptosis Regulatory Proteins; Autoimmune Diseases and Conditions; Blood Cells; Bone Marrow Cells; Caspase; Caspases; Cell Research; Cysteine Endopeptidases; Cysteine Proteases; Cytokines; Enzymes and Coenzymes; Genetics; Health and Medicine; Hemic and Immune Systems; Immunology; Initiator Caspases; Intercellular Signaling Peptides and Proteins; Interferons; Intracellular Signaling Peptides and Proteins; Lupus; Monocytes; Mononuclear Leukocytes; Mononuclear Phagocyte System; Myeloid Cells; Peptide Hydrolases; Peptides; Phagocytes; Systemic Lupus Erythematosus EN Fukuoka Japan Asia Apoptosis Regulatory Proteins Autoimmune Diseases and Conditions Blood Cells Bone Marrow Cells Caspase Caspases Cell Research Cysteine Endopeptidases Cysteine Proteases Cytokines Enzymes and Coenzymes Genetics Health and Medicine Hemic and Immune Systems Immunology Initiator Caspases Intercellular Signaling Peptides and Proteins Interferons Intracellular Signaling Peptides and Proteins Lupus Monocytes Mononuclear Leukocytes Mononuclear Phagocyte System Myeloid Cells Peptide Hydrolases Peptides Phagocytes Systemic Lupus Erythematosus 421 421 1 04/24/23 20230428 NES 230428 2023 APR 28 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- Researchers detail new data in Autoimmune Diseases and Conditions - Lupus. In this study, we aimed to identify the main cell types activating inflammasome in autoimmune diseases and to clarify the intracellular pathway of inflammasome activation in systemic lupus erythematosus (SLE).". [Extracted from the article]