Passion fruit peel pectin/chitosan based antibacterial films incorporated with biosynthesized silver nanoparticles for wound healing application.

Antimicrobial pectin/chitosan composite films have potential as wound dressing and food packaging. However, almost biofilms were synthesized through chemical routes, causing eco-unfriendliness, and negative impacts on the environment and human health. Green synthesis of composite films incorporating with biosynthesized AgNPs is therefore necessary to enhance mechanical and antimicrobial activities. This study focused on the influence of biosynthesized AgNPs on characteristics of passion fruit peel pectin/chitosan (P/CH) biofilms. Characterization, mechanical, antimicrobial activities of P/CH/AgNPs biofilms were evaluated. Incorporating AgNPs into P/CH-based films significantly exerted apparent color and optical properties of biofilms. As AgNPs concentration increased, P/CH/AgNPs biofilms had higher water content (20.1%), better water vapor permeability (1.28 × 10^–9 g/mm h Pa), but lower mechanical, water solubility (43.98%), swelling (630.29 ± 11.79%) indexes. P/CH/AgNPs biofilms exhibited outstanding antibacterial properties against S. aureus , B. cereus, P. aeruginosa, K. pneumonia. As expected, in vivo results consolidated the evidence of excellent wound closure (100%) of P/CH/AgNPs biofilms after 15 days. Our findings recommend P/CH/AgNPs antibacterial biofilms have promising biomedical applications. [ABSTRACT FROM AUTHOR]