Role of multiparametric MRI in characterization of complicated cystic renal masses.

Background: Bosniak classification improves sensitivity and specificity for malignancy among cystic renal masses characterized with MRI. The quantitative parameters derived from diffusion-weighted imaging, and contrast enhancement, can be used in distinguishing between benign and malignant cystic renal masses. Methods: This prospective observational study included 58 patients (39 male and 19 female) with complicated cystic renal mass initially diagnosed by US or CT. All patients underwent multiparametric MRI study (Pre- and Post-Gd-enhanced T1WI, T2WI and DWI) by using 3 Tesla MRI scanner. Each cystic renal lesion was assigned a category based on Bosniak classification. Demographic data were recorded. ADC ratio, dynamic enhancement parameters in both corticomedullary and nephrographic phases as well as absolute washout were calculated and compared using ROC curve analysis. Results: The sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy of the multiparametric MRI in categorization of cystic renal masses according to Bosniak classification version 2019 were 90.32%, 100%, 100%, 90% and 94.83%, respectively, which was higher compared to biparametric MRI and conventional MRI. Conclusions: Multiparametric MRI can be utilized to confidently evaluate cystic renal masses, overcoming the traditional limitations of overlapping morphological imaging features. Quantitative parameters derived from multiparametric MRI allow better evaluation of complex cystic renal tumors to distinguish between benign and malignant complex cystic renal lesions. [ABSTRACT FROM AUTHOR]