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Photodynamic Diagnosis-Assisted Transurethral Resection -- Lights Out?

Authors :
Dahm, Philipp
Narayan, Vikram M.
Source :
NEJM Evidence; Oct2022, Vol. 1 Issue 10, p1-1, 1p
Publication Year :
2022

Abstract

In a randomized trial and accompanying cost-effectiveness analysis, conducted in people with suspected urothelial carcinoma of the bladder, Heer at al. in this issue of NEJM Evidence compare transurethral resection aided by intravesical installation of a photosensitizer with the same procedure guided by standard white light. The study's main finding was that the photosensitizer-based approach was not associated with a reduction of time to recurrence of tumor. Moreover, patients undergoing the photosensitizer-based procedure had only a small absolute risk reduction (3.8 percentage points; 95% confidence interval [CI], -13.4 to 6.6) of tumor recurrence in the trial time frame. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
27665526
Volume :
1
Issue :
10
Database :
Supplemental Index
Journal :
NEJM Evidence
Publication Type :
Academic Journal
Accession number :
162525879
Full Text :
https://doi.org/10.1056/EVIDe2200194