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Design, Synthesis, and Biological Evaluation of Heterocyclic-Fused Pyrimidine Chemotypes Guided by X‑ray Crystal Structure with Potential Antitumor and Anti-multidrug Resistance Efficacy Targeting the Colchicine Binding Site.
- Source :
- Journal of Medicinal Chemistry; 3/9/2023, Vol. 66 Issue 5, p3588-3620, 33p
- Publication Year :
- 2023
Details
- Language :
- English
- ISSN :
- 00222623
- Volume :
- 66
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Journal of Medicinal Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 162377556
- Full Text :
- https://doi.org/10.1021/acs.jmedchem.2c02115