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Intestinal twin-to-twin transplant for short gut: Review of the literature and discussion of a complex case.
- Source :
- Medical & Surgical Pediatrics / Pediatria Medica e Chirurgica; 2022, Vol. 44 Issue 2, p8-12, 5p
- Publication Year :
- 2022
-
Abstract
- Paediatric Intestinal Transplantation (IT) presents the highest mortality on the waiting-list due to anatomical disproportion. Living-Donor IT (LDIT) offers the best advantages and when performed among identical monozygotic twins, it also benefits from unique immunology. According to MEDLINE/Pubmed, twin-to-twin LDIT has been performed in seven cases (6:7 males, median age of 32 years). None of the patients received immunosuppression postoperatively. Only one paediatric paediatric twin-to-twin LDIT was carried out with a 160-cm mid-ileum tract: an interposed 4/5-cm arterial graft was required to ensure a tensionfree anastomosis to the anterior wall of the infra-renal abdominal aorta. In contrast, venous anastomosis was done directly to the inferior cava vein. We present a case for debate of a 13-month-old SBS patient where a twin-LDIT was discussed with parents, who decided to wait after careful analysis and ethical considerations. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03915387
- Volume :
- 44
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Medical & Surgical Pediatrics / Pediatria Medica e Chirurgica
- Publication Type :
- Academic Journal
- Accession number :
- 162221632
- Full Text :
- https://doi.org/10.4081/pmc.2022.287