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Intestinal twin-to-twin transplant for short gut: Review of the literature and discussion of a complex case.

Authors :
Ugolini, Sara
Coletta, Riccardo
Morabito, Antonino
Source :
Medical & Surgical Pediatrics / Pediatria Medica e Chirurgica; 2022, Vol. 44 Issue 2, p8-12, 5p
Publication Year :
2022

Abstract

Paediatric Intestinal Transplantation (IT) presents the highest mortality on the waiting-list due to anatomical disproportion. Living-Donor IT (LDIT) offers the best advantages and when performed among identical monozygotic twins, it also benefits from unique immunology. According to MEDLINE/Pubmed, twin-to-twin LDIT has been performed in seven cases (6:7 males, median age of 32 years). None of the patients received immunosuppression postoperatively. Only one paediatric paediatric twin-to-twin LDIT was carried out with a 160-cm mid-ileum tract: an interposed 4/5-cm arterial graft was required to ensure a tensionfree anastomosis to the anterior wall of the infra-renal abdominal aorta. In contrast, venous anastomosis was done directly to the inferior cava vein. We present a case for debate of a 13-month-old SBS patient where a twin-LDIT was discussed with parents, who decided to wait after careful analysis and ethical considerations. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03915387
Volume :
44
Issue :
2
Database :
Supplemental Index
Journal :
Medical & Surgical Pediatrics / Pediatria Medica e Chirurgica
Publication Type :
Academic Journal
Accession number :
162221632
Full Text :
https://doi.org/10.4081/pmc.2022.287