Arterial stiffness and obstruction in western Mexican healthy population and patients with type 2 diabetes, a cross-sectional study.

Background: Nowadays does not exist enough studies related with cutoff points of arterial stiffness and obstruction in Mexican population compared with patients with T2DM [1]; also, is important to have a landmark on these clinical assessments to identify arterial stiffness and obstruction timely to provide also an early treatment [2-3]. Aim: To identify cutoff points, differences and correlations of arterial stiffness and obstruction between healthy/T2DM population. Methods: In a cross-sectional study, a total of 296 western Mexican individuals (163 healthy, 133 with T2DM according with ADA 2022 [4])were enrolled, aged 40-65 years (mean 52.7 ± 6.6). Variables like sex, BMI, baPWV and ankle-brachial index (ABI) were measured. T-student was used for equality of means and Pearson's test for correlation. Results: When comparing groups (healthy/T2DM), there was not a significative difference on age (52.07 ± 6.30, 53.59 ± 0.09, p:0.052) and ABI (1.12 ± 0.07, 1.13 ± 0.13, p:0.55); we found a significative difference on BMI (25.96 ± 3.29, 29.41 ± 5.08, p: < 0.01), beats/min (62.17 ± 10.63, 70.5 ± 13.3, p: < 0.01) and baPWV (1310.31 ± 186.75, 1595.33 ± 321.99, p: < 0.01); additionally there were a significative correlation between age & baPWV (r = 0.358, p: < 0.01) and baPWV & ABI (r = 0.188, p: < 0.01). Conclusion: We found a greater arterial stiffness in T2DM patients, BMI and beats/min; also, a correlation between age, ABI with arterial stiffness; and there were not differences between healthy/T2DM on ABI, and provide cutoff points for further studies. [ABSTRACT FROM AUTHOR]