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Hiding Payload Inside the IgG Fc Cavity Significantly Enhances the Therapeutic Index of Antibody–Drug Conjugates.

Authors :
Shi, Wei
Zhang, Jianxin
Liu, Liya
Li, Wanzhen
Liu, Zhi
Ren, Anni
Wang, Jie
Tang, Caihong
Yang, Yang
Xu, Dandan
Huang, Qianqian
Wang, Yongqin
Luo, Caili
Huang, Wei
Tang, Feng
Source :
Journal of Medicinal Chemistry; 1/12/2023, Vol. 66 Issue 1, p1011-1026, 16p
Publication Year :
2023

Details

Language :
English
ISSN :
00222623
Volume :
66
Issue :
1
Database :
Supplemental Index
Journal :
Journal of Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
161325701
Full Text :
https://doi.org/10.1021/acs.jmedchem.2c01812