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Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design.

Authors :
Hidetomo Yokoo
Norihito Shibata
Akinori Endo
Takahito Ito
Yuta Yanase
Yuki Murakami
Kiyonaga Fujii
Kengo Hamamura
Yasushi Saeki
Mikihiko Naito
Kosuke Aritake
Yosuke Demizu
Source :
Journal of Medicinal Chemistry; 11/11/2021, Vol. 64 Issue 21, p15868-15882, 15p
Publication Year :
2021

Details

Language :
English
ISSN :
00222623
Volume :
64
Issue :
21
Database :
Supplemental Index
Journal :
Journal of Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
156368397
Full Text :
https://doi.org/10.1021/acs.jmedchem.1c01206