Discovery of 9‑Cyclopropylethynyl-2-((S)‑1-[1,4]dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1‑a]-isoquinolin-4-one (GLPG1205), a Unique GPR84 Negative Allosteric Modulator Undergoing Evaluation in a Phase II Clinical Trial.

Details

Language :

English

ISSN :

00222623

Volume :

63

Issue :

22

Database :

Supplemental Index

Journal :

Journal of Medicinal Chemistry

Publication Type :

Academic Journal

Accession number :

147225829

Full Text :

https://doi.org/10.1021/acs.jmedchem.0c00272