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Pulmonary fibrosis in critical ill patients recovered from COVID-19 pneumonia: Preliminary experience.
- Source :
- American Journal of Emergency Medicine; Oct2020, Vol. 38 Issue 10, p2134-2138, 5p
- Publication Year :
- 2020
-
Abstract
- <bold>Objective: </bold>To investigate chest computed tomography (CT) findings associated with severe COVID-19 pneumonia in the early recovery period.<bold>Methods: </bold>We retrospectively analyzed the cases of patients diagnosed with severe COVID-19 pneumonia at a single center between January 12, 2020, and March 16, 2020. The twelve ICU patients studied had been diagnosed SARS-CoV-2 (COVID-19) nucleic acid positive. Patient clinical symptoms were relieved or disappeared, and basic clinical information and laboratory test results were collected. The study focused on the most recent CT imaging characteristics.<bold>Results: </bold>The average age of the 12 patients was 58.8 ± 16.2 years. The most prevalent symptoms were fever (100%), dyspnea (100%), and cough (83.3%). All patients experienced acute respiratory distress syndrome (ARDS), of which 9 were moderate to severe. Six patients used noninvasive ventilators, and 4 patients used mechanical ventilation. One patient was treated with extracorporeal membrane oxygenation (ECMO). The lymphocyte count decreased to 0.67 ± 0.3 (× 10 9/L). The average day from illness onset to the last follow-up CT was 56.1 ± 7.7 d. The CT results showed a decrease in ground glass opacities (GGO), whereas fibrosis gradually increased. The common CT features included GGO (10/12, 83.3%), subpleural line (10/12, 83.3%), fibrous stripes (12/12, 100%), and traction bronchiectasis (10/12, 83.3%). Eight patients (66.7%) showed predominant reticulation and interlobular thickening. Four patients (33.3%) showed predominant GGO. Lung segments involved were 174/216 (80.6%).<bold>Conclusions: </bold>Fibrous stripes and GGO are common CT signs in critically ill patients with COVID-19 pneumonia in the early recovery period. Signs of pulmonary fibrosis in survivors should be carefully monitored. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 07356757
- Volume :
- 38
- Issue :
- 10
- Database :
- Supplemental Index
- Journal :
- American Journal of Emergency Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 147201175
- Full Text :
- https://doi.org/10.1016/j.ajem.2020.05.120