Green synthesis of magnetic nanoparticles via Cinnamomum verum bark extract for biological application.

• The phytomediate synthesis of Fe nanoparticles have performed with Cinnamomum verum bark extract. • Spherically 20-80 nm sized Fe nanoparticles shown better inhibition upon E. coli , K. pneumonia , S. aureus and B. subtilis. • The antioxidant, anti-inflammatory, anti-diabetic assays shown the efficient inhibition than positive control. The green synthesis of magnetic Fe nanoparticles (NPs) was prepared via Cinnamomum Verum bark extract. The UV–vis analysis explained the formation of Fe NPs with SPR band at 288 nm. The powder X-ray diffraction analysis (XRD) explicated the mean crystallite size was at 36 nm. The Fourier Transform Infra-Red analysis (FTIR) revealed the functional groups in the prepared Fe NPs. The Scanning Electron Microscope (SEM) and High-Resolution Transmission Electron Microscope (HR-TEM) analyses notified the circular and spherical shaped Fe NPs with the size at 20−50 nm. The Energy dispersive X-ray spectroscopy (EDS) and mapping analyses validated the formation of Fe NPs with purity. The Vibrating Sample Magnetometer (VSM) revealed the paramagnetic behavior of prepared Fe NPs. The phytochemical analysis described the phytochemicals compounds which present in Cinnamomum Verum bark extract. The Antibacterial assay described the much higher inhibition zone of prepared Fe NPs upon human pathogenic bacteria. The Antioxidant (DPPH) assay described the efficient scavenging behavior of Fe NPs with 89 % at 80 μg/mL concentration. The Anti-inflammatory assay explicated the potential protein denaturation behavior of Fe NPs with 87 % at 500 μg/mL concentration. The Anti-diabetic assay reported the much higher potential efficiency of prepared Fe NPs with 84 % at 500 μg/mL concentration. [ABSTRACT FROM AUTHOR]