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Cryogel biocomposite containing chitosan-gelatin/cerium–zinc doped hydroxyapatite for bone tissue engineering.
- Source :
- Saudi Journal of Biological Sciences; Oct2020, Vol. 27 Issue 10, p2638-2644, 7p
- Publication Year :
- 2020
-
Abstract
- The present examination includes manufacture and portrayal of cryogel bio-composite implants containing chitosan-gelatin (CS-GT), cerium–zinc doped hydroxyapatite (CS-GT/Ce-Zn-HA) by cryogelation technique. The prepared cryogel biocomposites (CS-GT/HA and CS-GT/Ce-Zn-HA) were described by scanning electron microscope (SEM) and X-Ray diffraction (XRD) contemplates. The expansion of Ce-Zn in the CS-GT implants essentially expanded growing, diminished swelling, expanded protein sorption, and expanded bactericidal movement. The CS-GT/Ce-Zn-HA biocomposite had non-toxic towards rodent osteoblast cells. So the created CS-GT/Ce-Zn-HA biocomposite has favorable and potential applications over the CS-GT/HA platforms for bone tissue engineering. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 1319562X
- Volume :
- 27
- Issue :
- 10
- Database :
- Supplemental Index
- Journal :
- Saudi Journal of Biological Sciences
- Publication Type :
- Academic Journal
- Accession number :
- 145681694
- Full Text :
- https://doi.org/10.1016/j.sjbs.2020.05.045