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Reducing the Lipophilicity of Perfluoroalkyl Groups by CF2-F/CF2-Me or CF3/CH3 Exchange.

Authors :
Jeffries, Benjamin
Wang, Zhong
Graton, Jérôme
Holland, Simon D.
Brind, Thomasin
Greenwood, Ryan D. R.
Le Questel, Jean-Yves
Scott, James S.
Chiarparin, Elisabetta
Linclau, Bruno
Source :
Journal of Medicinal Chemistry; 12/13/2018, Vol. 61 Issue 23, p10602-10618, 17p
Publication Year :
2018

Details

Language :
English
ISSN :
00222623
Volume :
61
Issue :
23
Database :
Supplemental Index
Journal :
Journal of Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
145486920
Full Text :
https://doi.org/10.1021/acs.jmedchem.8b01222