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Parry Romberg syndrome: Imaging features in 4 consecutive cases and review of literature.

Authors :
Ahmed, Sabha
Tiwari, Sarbesh
Yadav, Taruna
Khera, Pushpinder Singh
Garg, Pawan
Sureka, Binit
Budania, Anil
Singh, Saurabh
Source :
Journal of Clinical Neuroscience; Jun2020, Vol. 76, p249-253, 5p
Publication Year :
2020

Abstract

• Parry Romberg syndrome is a neurocutaneous disease characterized by facial hemiatrophy and variable neurological symptoms like seizure disorder and headache. • Ipsilateral cerebral hemi atrophy, abnormal white matter T2 hyperintensities and intra-parenchymal calcification are the most frequent neuroimaging abnormality. • Parry Romberg Syndrome and linear scleroderma represents the spectrum of same disease and differentiation maybe difficult. Parry Romberg syndrome (PRS) is a distinct sporadic self-limiting entity comprising progressive hemi- atrophy of the face with predisposition to affect the skin, subcutaneous tissue and in some cases deeper extension to the cartilage, osseous structures and musculature (Wong et al., 2015; Aydın et al., 2015; Sharma et al., 2012) [1–3]. Neurologic and ocular involvement is variable as is the progression of this entity. With a multitude of aetiologies ranging from autoimmune to infectious this syndrome is a diagnosis of exclusion, with a highly variable prognosis, drawing the amusement of radiologists and clinicians. Radiological assessment and subsequent diagnosis of this entity can aid in alleviating the lifestyle hampering progression of this disease process. We hereby report 4 cases of this syndrome and aim to describe the varied radiological presentations of this entity with concise review of literature. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09675868
Volume :
76
Database :
Supplemental Index
Journal :
Journal of Clinical Neuroscience
Publication Type :
Academic Journal
Accession number :
143554117
Full Text :
https://doi.org/10.1016/j.jocn.2020.04.024