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Effects of berberine and barberry on anthropometric measures: A systematic review and meta-analysis of randomized controlled trials.

Authors :
Amini, Mohammad Reza
Sheikhhossein, Fatemeh
Naghshi, Sina
Djafari, Farhang
Askari, Mohammadreza
Shahinfar, Hossein
Safabakhsh, Maryam
Jafari, Alireza
Shab-Bidar, Sakineh
Source :
Complementary Therapies in Medicine; Mar2020, Vol. 49, pN.PAG-N.PAG, 1p
Publication Year :
2020

Abstract

<bold>Objective: </bold>Despite controversies, no study has systematically summarized findings from earlier studies on the effect of berberine and barberry on anthropometric measures. Therefore, the current systematic review and meta-analysis was conducted on the effect of berberine and barberry on body mass index (BMI), body weight (BW), waist circumference (WC) and waist-hip ratio (WHR) in adults.<bold>Methods: </bold>Relevant studies, published up to August 2019, were searched through PubMed/Medline, Scopus, ISI Web of Science, Embase and Google Scholar. All randomized clinical trials investigating the effect of berberine and barberry on the anthropometric measures including BMI, BW, WC or/and WHR were included.<bold>Results: </bold>Out of 252 citations, 12 trials that enrolled 849 subjects were included. Berberine and barberry resulted in no significant change in BMI (Weighted mean differences (WMD): -0.16 kg/m2; 95 % CI: -0.43 to 0.11, P = 0.247), BW (WMD: -0.11 kg; 95 % CI: -0.13 to 0.91, P = 0.830), and berberine resulted in not significant in WC (WMD: -0.58 cm; 95 % CI: -1.89 to 0.72, P = 0.379) and significant reduction in WHR (WMD: -0.03; 95 % CI: -0.04 to -0.01, P < 0.0001).<bold>Conclusion: </bold>We found a significant reduction in WHR following berberine consumption in adults. Further clinical trials with high quality according to challenges mentioned seem to be helpful to use berberine and barberry as a supplement for certain health conditions, efficiently. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09652299
Volume :
49
Database :
Supplemental Index
Journal :
Complementary Therapies in Medicine
Publication Type :
Academic Journal
Accession number :
142108624
Full Text :
https://doi.org/10.1016/j.ctim.2020.102337