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Coronary artery disease in a child with homozygous familial hypercholesterolemia: Regression after liver transplantation.
- Source :
- Journal of Clinical Lipidology; Nov2019, Vol. 13 Issue 6, p880-886, 7p
- Publication Year :
- 2019
-
Abstract
- Children with homozygous familial hypercholesterolemia are at risk for early cardiovascular events secondary to coronary artery disease. Current medical therapy does not ameliorate this risk. Liver transplantation offers the most effective option to reduce circulating levels of low-density lipoprotein cholesterol and thereby reduce risk of cardiovascular events. Angiographic evidence of regression of coronary artery disease is presented. • Current therapy for homozygous FH does not result in persistently normal LDL-c levels. • Contrast cCTA may provide a reliable assessment of atherosclerosis. • Study of QOL during apheresis and after liver transplantation in children is needed. • Coronary artery atherosclerosis may regress after liver transplantation. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 19332874
- Volume :
- 13
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- Journal of Clinical Lipidology
- Publication Type :
- Academic Journal
- Accession number :
- 140294192
- Full Text :
- https://doi.org/10.1016/j.jacl.2019.09.007