Back to Search Start Over

Natural products against cancer: Review on phytochemicals from marine sources in preventing cancer.

Authors :
Wali, Adil Farooq
Majid, Sabhiya
Rasool, Shabhat
Shehada, Samar Bassam
Abdulkareem, Shahad Khalid
Firdous, Aimen
Beigh, Saba
Shakeel, Sheeba
Mushtaq, Saima
Akbar, Imra
Madhkali, Hassan
Rehman, Muneeb U.
Source :
Saudi Pharmaceutical Journal; Sep2019, Vol. 27 Issue 6, p767-777, 11p
Publication Year :
2019

Abstract

Marine natural products have as of now been acknowledged as the most important source of bioactive substances and drug leads. Marine flora and fauna, such as algae, bacteria, sponges, fungi, seaweeds, corals, diatoms, ascidian etc. are important resources from oceans, accounting for more than 90% of the total oceanic biomass. They are taxonomically different with huge productive and are pharmacologically active novel chemical signatures and bid a tremendous opportunity for discovery of new anti-cancer molecules. The water bodies a rich source of potent molecules which improve existence suitability and serve as chemical shield against microbes and little or huge creatures. These molecules have exhibited a range of biological properties antioxidant, antibacterial, antitumour etc. In spite of huge resources enriched with exciting chemicals, the marine floras and faunas are largely unexplored for their anticancer properties. In recent past, numerous marine anticancer compounds have been isolated, characterized, identified and are under trials for human use. In this write up we have tried to compile about marine-derived compounds anticancer biological activities of diverse flora and fauna and their underlying mechanisms and the generous raise in these compounds examined for malignant growth treatment in the course of the most recent quite a long while. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13190164
Volume :
27
Issue :
6
Database :
Supplemental Index
Journal :
Saudi Pharmaceutical Journal
Publication Type :
Academic Journal
Accession number :
138317463
Full Text :
https://doi.org/10.1016/j.jsps.2019.04.013