A Meta-Analytical Review of Muscle Glycogen Replenishment.

This study determined the mechanisms of muscle glycogen depletion and replenishment. A systematic literature review and meta-analysis research design was used. Inclusion and exclusion criteria consisted of the following: Glycogen depletionreplenishment studies; subjects in studies had no pathologies; human and animal studies were accepted; studies with diet manipulation were accepted; articles accepted for coding were peer reviewed, original publications. Coded studies were summarized and statistically analyzed. Coded variables were presented as means and standard deviations (±SD). Muscle glycogen depletion and replenishment were analyzed with Cohen's d effect size (ES). Fourteen studies were coded allowing for a total sample size of N=149. Subject demographics were: age, 29.0 ± 2.9 yrs; height, 180.4 ± 5) cm; and weight, 74.7 ± 3.6 kg. Pre-Post depletion rate ES was 10.29, which was considered huge. Post replenishment rate ES was 4.39, which was considered large. High intensity work led to the greatest depletion rates. High carbohydrates, with high kcal per meal showed the greatest replenishment rates. [ABSTRACT FROM AUTHOR]