Bilateral Uveal Metastasis Due to a Mammary Carcinoma in a Rabbit: A Case Report.

A 5-year-old intact female rabbit was presented with bilateral ocular lesions. In both eyes, a fleshy mass was emerging from the iris. Focal corneal edema, neovascularization, generalized rubeosis iridis, +1 aqueous flare, and dyscoria could also be identified. In addition, hepatomegaly was detected by clinical examination. Hematology and serum biochemistry results included leukocytosis, slight anemia, hyperproteinemia, and mild increased liver enzyme activities. Abdominal ultrasound revealed a moderate enlarged liver with a heterogeneous structure as well as ascites. Thoracic radiography showed generalized pulmonary metastasis. By request of the owner, the rabbit was euthanized. Pathological examination revealed nodules composed of malignant epithelial cells in the lung, anterior and posterior uvea of both eyes, pericardium, diaphragm, liver, mammary gland, and the left ovary. A carcinoma of the mammary gland was suspected as the primary tumor. To our knowledge, this is the first report of a carcinoma with bilateral uveal metastasis in a rabbit. [ABSTRACT FROM AUTHOR]