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Sarcopenia is an effective prognostic indicator of postoperative outcomes in laparoscopic-assisted gastrectomy.
- Source :
- European Journal of Surgical Oncology; Jun2019, Vol. 45 Issue 6, p1092-1098, 7p
- Publication Year :
- 2019
-
Abstract
- The association between sarcopenia and postoperative outcomes in patients who undergo laparoscopic-assisted gastrectomy is unclear. We aimed to determine the predictive value of sarcopenia for adverse postoperative outcomes after laparoscopic-assisted gastrectomy for gastric cancer. We prospectively collected the clinical data of patients who underwent elective radical laparoscopic-assisted gastrectomy for gastric cancer in two large centers from August 2014 to October 2017. The third lumbar vertebra skeletal muscle index, handgrip strength, and 6-m usual gait speed were measured to diagnose sarcopenia. Subsequently, we aimed to identify the risk factors for postoperative complications. The study included 313 patients and 37 (11.8%) patients were classified as sarcopenic. Compared with non-sarcopenic patients, sarcopenic patients were significantly older (P < 0.001), had higher nutritional risk screening 2002 scores (P = 0.013), Charlson comorbidity index (CCI) scores (P = 0.033), and neutrophil to lymphocyte ratio (P = 0.004), and lower body mass index (P < 0.001), preoperative serum albumin (P < 0.001), and hemoglobin (P < 0.001). Sarcopenic patients had higher postoperative complication rate (P = 0.002), longer postoperative hospital stays (P = 0.020) and higher total cost of hospitalization (P = 0.001). Multivariate analysis revealed that CCI score ≥1 (odds ratio [OR]: 2.424, 95% confidence interval [CI]: 1.309–4.487; P = 0.005) and sarcopenia (OR: 2.752, 95% CI: 1.274–5.944; P = 0.010) were independent risk factors for short-term postoperative complications. Sarcopenia is an independent clinical predictor of short-term postoperative complications after laparoscopic-assisted gastrectomy. [ABSTRACT FROM AUTHOR]
- Subjects :
- SARCOPENIA
SURGICAL complications
BODY mass index
LUMBAR vertebrae
STOMACH cancer
Subjects
Details
- Language :
- English
- ISSN :
- 07487983
- Volume :
- 45
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- European Journal of Surgical Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 136498525
- Full Text :
- https://doi.org/10.1016/j.ejso.2018.09.030