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Expression of the genes encoding hypothalamic feeding-related neuropeptides in the streptozotocin-induced diabetic rats with variable hyperglycemia and hyperphagia.

Authors :
Sonoda, Satomi
Yoshimura, Mitsuhiro
Ueno, Hiromichi
Nishimura, Haruki
Nishimura, Kazuaki
Tanaka, Kentaro
Motojima, Yasuhito
Saito, Reiko
Maruyama, Takashi
Hashimoto, Hirofumi
Okada, Yosuke
Tanaka, Yoshiya
Ueta, Yoichi
Source :
Neuropeptides; Jun2019, Vol. 75, p34-40, 7p
Publication Year :
2019

Abstract

• We examined the hypothalamic feeding-related neuropeptides in diabetic rats. • STZ-induced diabetic rats exhibit hyperphagia in a blood glucose dependent manner. • Dynamic regulation of these genes was associated with plasma glucose/insulin. • These genes were differentially expressed depending on the glucose/insulin. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
01434179
Volume :
75
Database :
Supplemental Index
Journal :
Neuropeptides
Publication Type :
Academic Journal
Accession number :
136351261
Full Text :
https://doi.org/10.1016/j.npep.2019.03.003