Exfoliated nanosheets of Co3O4 webbed with polyaniline nanofibers: A novel composite electrode material for enzymeless glucose sensing application.

Highlights • Synthesized Cobalt oxide (Co 3 O 4) sheets are exfoliated into layered nanosheets. • Surface of the nanosheets are uniformly webbed by polyaniline nanofibers (PANINFs). • Co 3 O 4 @PANINFs material showed electrocatalytic property in electrochemical study. • The nanohybrid material is used for the fabrication of efficient glucose biosensor. Abstract A novel glucose biosensor was designed using cobalt oxide (Co 3 O 4) nanosheets patterned by π-conjugated polyaniline nanofibers (PANINFs). A facile synthesis process was conducted to obtain cost-effective and ecofriendly mesoporous Co 3 O 4 @PANINFs hybrid nanomaterial for the first time. The Co 3 O 4 @PANINFs on glassy carbon electrode (GCE), working as a biosensor electrode based on electrochemical technique, showed electrocatalytic activity to glucose with sensitivity of 14.25 μA mM⁻¹ cm⁻², linear range from (0.1 to 8) mM, minimum detection limit of 0.06 mM, and response time <6 s. Moreover, the biosensor was employed to monitor glucose concentration in human serum sample to provide effective sensing results. [ABSTRACT FROM AUTHOR]