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Relationships of depression and anxiety symptoms with seizure frequency: Results from a multicenter follow-up study.
- Source :
- Seizure; Dec2017, Vol. 53, p103-109, 7p
- Publication Year :
- 2017
-
Abstract
- <bold>Purpose: </bold>Depressive and anxiety disorders are frequent among people with epilepsies. There are, however, only few longitudinal studies, which examine the relationship between these comorbid psychiatric disorders and epilepsy-related variables. Thus, we investigated the interrelationships of depression and anxiety symptoms with seizure frequency across time.<bold>Methods: </bold>Before admittance to an epilepsy center (T1) and six months after discharge (T2), patients (n=198) with mainly difficult-to-treat epilepsies completed the Hospital Anxiety and Depression Scale (HADS). Correlation and path analyses were conducted.<bold>Results: </bold>Depression and anxiety symptoms (HADS) as well as seizure frequency significantly decreased from baseline to follow-up. Both at T1 and T2, seizure frequency was slightly, but significantly correlated with depression and anxiety levels (rs=0.17-.32). Cross-lagged-analyses showed that baseline (T1) level of depression significantly predicted frequency of seizures at follow-up (T2). However, anxiety at T1 was not a significant predictor of seizure frequency at T2 and seizure frequency at T1 did not predict either depressive or anxiety symptoms at T2.<bold>Conclusion: </bold>The present findings emphasize the importance of psychiatric comorbidities, especially depression, for seizure frequency and its progress in patients with difficult-to-treat epilepsies referred to a specialized epilepsy center. Thus, comorbid psychiatric disorders need specific consideration as part of a comprehensive diagnostic and therapeutic treatment approach. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10591311
- Volume :
- 53
- Database :
- Supplemental Index
- Journal :
- Seizure
- Publication Type :
- Academic Journal
- Accession number :
- 126559596
- Full Text :
- https://doi.org/10.1016/j.seizure.2017.11.008