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Crystal structures of NNRT-resistant HIV RT characterized.
- Source :
- Proteomics Weekly; 3/29/2004, p49-50, 2p
- Publication Year :
- 2004
-
Abstract
- Characterizes the crystal structures of several forms of NNRT-resistant HIV RT. Observation of leu100Ile, Val106Ala, and Val108Ile mutations in HIV-1 reverse transcriptase; Determination of crystal structures of mutant RT-inhibitor complexes; Observation of shifts in side-chain and inhibitor positions.
Details
- Language :
- English
- ISSN :
- 15352722
- Database :
- Supplemental Index
- Journal :
- Proteomics Weekly
- Publication Type :
- Periodical
- Accession number :
- 12628819