CO2-intensified Hydrolysis of Rutin to Quercetin – A Comparison of Experimental Data and modelled Reaction Kinetics.

This work describes the possibility to hydrolyze rutin (quercetin-3- O -rutinoside) to quercetin using carbon dioxide (CO 2 ) and water without the addition of acids or enzymes. Eight hours of CO 2 -intensified hydrolysis of aqueous rutin-solutions were carried out to investigate temperature (373.15 K–433.15 K) and pressure dependence (4–150 bar). Both temperature and CO 2 -pressure dependence are studied. The parameter combination of 413.15 K and 150 bar gave a complete (100 %) conversion of rutin to quercetin. Temperature and pressure dependence were modelled. Models achieved correlation coefficients between R 2 = 0.85 and 0.99. Influence of H + ions was described by implementing the »H + -factor« to explain the hydrolysis effect of CO 2 -pressure in more detail. The results of this work demonstrate that CO 2 -intensified hydrolysis is possible at moderate temperatures and pressures. [ABSTRACT FROM AUTHOR]