Reduction in Butyrylcholinesterase Activity and Cardiovascular Risk Factors in Obese Adolescents after 12-Weeks of High-Intensity Interval Training.

The purpose of this study was to evaluate the effect of 12 wks of high-intensity interval training (HIIT) on butyrylcholinesterase (BChE) and cardiovascular risk factors in obese adolescents. The subjects were 54 obese adolescents, divided into two groups: the high-intensity interval training group (HIITG, n = 20) and the control group (CG, n = 34). The HIIT resulted in a significant decrease in BMI z-score, WC, TC, LDL-C and BChE activity (P<0.05). The CG showed a significant increase in BChE (P = 0.05) with no change in BMI, BMI z-score, CC, TC, LDL-C, HDL-C and TG. The decrease in BChE activity with HIIT training was accompanied by the decrease in biochemical markers, thus indicating that the BChE activity can be used as a secondary marker for cardiovascular risk factors that are associated with child and adolescent obesity. [ABSTRACT FROM AUTHOR]