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Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR...
- Source :
- Journal of Medicinal Chemistry; 4/13/2017, Vol. 60 Issue 7, p3002-3019, 18p
- Publication Year :
- 2017
Details
- Language :
- English
- ISSN :
- 00222623
- Volume :
- 60
- Issue :
- 7
- Database :
- Supplemental Index
- Journal :
- Journal of Medicinal Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 122530052
- Full Text :
- https://doi.org/10.1021/acs.jmedchem.6b01894