The impact of narrow band imaging in detecting recurrence during NMIBC follow-up.

Introduction: The present study was aimed to assess in a retrospective manner the impact of narrow band imaging (NBI) cystoscopy concerning the detection of recurrent tumors during the follow-up protocol for previously confirmed non-muscle invasive bladder cancer (NMIBC) patients. Materials and Methods: Between June 2014 and January 2015, a total of 45 known NMIBC cases (based on the initial pathology findings subsequent to standard transurethral resection of bladder tumors - TURBT) were confirmed as presenting tumor recurrence. All cases underwent both standard white light (WLC) and NBI cystoscopy, followed by the classical resection of all WLC detected tumors and NBI guided TURBT for lesions solely observed in NBI vision. Results: In light of the pathological exam, 43 cases were diagnosed with NMIBC recurrence (2 patients had muscle invasive tumors and were excluded from the analysis). The NBI mode was characterized by a higher patients' detection rate when compared to conventional cystoscopy (95.3% versus 83.7%). On a lesions' related basis, the NBI evaluation also displayed an improved diagnostic accuracy by comparison to white light (91.5% versus 79.7%). On the other hand, NBI cystoscopy was marked by an increased rate of false positive results (19.2% versus 13.2%). Conclusions: The use of NBI assessment during the periodical cystoscopic NMIBC follow-up was confirmed to benefit from superior sensitivity leading to more recurrent tumors being identified and resected. [ABSTRACT FROM AUTHOR]