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Solvent-mediated Tuning of the Regioselectivity of Intramolecular Diaryl Ether Formation: Total Synthesis of (+)-Aspercyclide C.

Authors :
Tatsuya Yoshino
Shuji Yamashita
Itaru Sato
Yujiro Hayashi
Masahiro Hirama
Source :
Chemistry Letters; 3/5/2014, Vol. 43 Issue 3, p349-351, 3p
Publication Year :
2014

Abstract

A concise total synthesis of the 11-membered cyclic (+)-aspercyclide C is reported. Key to success was the finetuning of the reaction media to realize an oxidative, macrocyclic diaryl C-O bond formation in a regioselective and direct fashion. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03667022
Volume :
43
Issue :
3
Database :
Supplemental Index
Journal :
Chemistry Letters
Publication Type :
Academic Journal
Accession number :
120716882
Full Text :
https://doi.org/10.1246/cl.131045