Ethyl Imidazole-1-carboxylate (EImC) as a Carbonylating Agent: Efficient Synthesis of Oxazolidin-2-ones from Amino Alcohols.

Various substituted oxazolidin-2-ones were synthesized from the corresponding amino alcohols using ethyl imidazole-1-carboxylate (EImC). Highly substituted and sterically hindered amino alcohols and amino alcohols having a free hydroxy group were cyclized to oxazolidin-2-ones efficiently. This method is simple and produces oxazolidin-2-ones in very good yield. [ABSTRACT FROM AUTHOR]