Chronic skin lichenification as an unusual presentation of eosinophilic granulomatosis with polyangiitis: case report and literature review.

Eosinophilic granulomatosis with polyangiitis (EGPA) is an uncommon ANCA-associated systemic small-vessel necrotizing vasculitis. At times, EGPA presenting mani festations can be very different from the usually re cognized disease patterns. We report a 52-year-old female patient with 3 years history of itching. In this period, the patient developed chronic skin lichenification on her legs followed by full-blown ANCA-MPO positive EGPA in combination with blood hypereo sinophilia, eosinophilic vasculitis at skin biopsy, subclinical asthma and chronic rhinosinusitis. [ABSTRACT FROM AUTHOR]