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Discovery of a Selective and Potent Inhibitor of Mitogen-Activated Protein Kinase-Interacting Kinases 1 and 2 (MNK1/2) Utilizing Structure-Based Drug Design.

Authors :
Wooseok Han
Yu Ding
Yongjin Xu
Pfister, Keith
Shejin Zhu
Warne, Bob
Doyle, Mike
Mina Aikawa
Amiri, Payman
Appleton, Brent
Stuart, Darrin D.
Fanidi, Abdallah
Shafer, Cynthia M.
Source :
Journal of Medicinal Chemistry; 4/14/2016, Vol. 59 Issue 7, p3034-3045, 12p
Publication Year :
2016

Details

Language :
English
ISSN :
00222623
Volume :
59
Issue :
7
Database :
Supplemental Index
Journal :
Journal of Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
115449406
Full Text :
https://doi.org/10.1021/acs.jmedchem.5b01657