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Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode.

Authors :
Sawatzky, Edgar
Wehle, Sarah
Kling, Beata
Wendrich, Jan
Bringmann, Gerhard
Sotriffer, Christoph A.
Heilmann, Jörg
Decker, Michael
Source :
Journal of Medicinal Chemistry; Mar2016, Vol. 59 Issue 5, p2067-2082, 16p
Publication Year :
2016

Details

Language :
English
ISSN :
00222623
Volume :
59
Issue :
5
Database :
Supplemental Index
Journal :
Journal of Medicinal Chemistry
Publication Type :
Academic Journal
Accession number :
114321978
Full Text :
https://doi.org/10.1021/acs.jmedchem.5b01674