Back to Search Start Over

A prospective randomized study comparing 25-G and 22-G needles of a new platform for endoscopic ultrasound-guided fine needle aspiration of solid masses.

Authors :
Carrara, Silvia
Anderloni, Andrea
Jovani, Manol
Di Tommaso, Luca
Rahal, Daoud
Hassan, Cesare
Ridola, Lorenzo
Federico, Davide
Loriga, Alessandra
Repici, Alessandro
Source :
Digestive & Liver Disease; Jan2016, Vol. 48 Issue 1, p49-54, 6p
Publication Year :
2016

Abstract

Background A new needle platform for endoscopic ultrasound-guided fine-needle aspiration biopsy has been developed that allows interchangeability of all needle sizes. Aims To prospectively compare the efficacy of the new 25-G needles and 22-G needles for obtaining an adequate aspirate of solid masses. Methods Randomized controlled trial of 144 patients referred for endoscopic ultrasound-guided fine-needle aspiration of solid pancreatic masses, intraparietal tumours, or lymph-nodes, randomized to the 25-G or 22-G needle arms. Results An adequate specimen was obtained from 74.3% of cases. The sample tended to be more adequate in the 25-G compared to the 22-G group (81% vs. 68%; p = 0.09). Crossover was required in 14 (19%) and 12 (17%) cases in the 22-G and in the 25-G groups, respectively ( p = 0.7). The overall rate of adequacy improved from 74% before crossover to 90% after crossover ( p < 0.01). When comparing the two groups after crossover, the rate of obtaining adequate samples was significantly higher in the 25-G arm than in the 22-G arm (95.8% vs. 86.1%; p = 0.03). Conclusions The 25-G needle was superior to the 22-G needle for endoscopic ultrasound-guided fine-needle aspiration biopsy. The adequacy and diagnostic accuracy improved after crossover, reaching 90%. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
15908658
Volume :
48
Issue :
1
Database :
Supplemental Index
Journal :
Digestive & Liver Disease
Publication Type :
Academic Journal
Accession number :
112628506
Full Text :
https://doi.org/10.1016/j.dld.2015.09.017