Early diffuse slowing on electroencephalogram in pediatric traumatic brain injury: Impact on management and prognosis.

Introduction We hypothesized that the finding of diffuse slowing on bedside EEG in children with moderate to severe traumatic brain injury (TBI) is associated with prolonged hospital stay and worse functional outcomes. Methods We reviewed the medical records of all patients admitted to a single level I pediatric trauma center with moderate or severe TBI from 1/10–12/12 (defined by GCS < 10 on admission). EEG monitoring results, patient demographics, clinical characteristics, length of stay and postinjury outcomes were recorded. We compared outcomes between patients with and without diffuse slowing on EEG. Data are presented as mean ± SEM; p < 0.05 was considered statistically significant. Results 219 children with TBI were identified; 81 had a bedside EEG performed within 48 hours of admission. Diffuse slowing was present in 50 (mean age 5.7 + 0.7 years) and absent in 31 (n = 31, mean age 4.2 + 0.9 years). Patients with diffuse slowing had a significant increase in ventilator days, ICU LOS, need for rehabilitation, and rehabilitation length of stay. Conclusion The presence of diffuse slowing on EEG in children with TBI is associated with prolonged patient recovery and poor functional outcomes. This finding should prompt early consideration for rehabilitation and the need for intensive therapy. [ABSTRACT FROM AUTHOR]