Discovery of N-(4-(3-(2-Aminopyrimidin-4-yl)pyridin-2-yloxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine(AMG 900), A Highly Selective, Orally Bioavailable Inhibitor of AuroraKinases with Activity against Multidrug-Resistant Cancer Cell Lines.

Details

Language :

English

ISSN :

00222623

Volume :

58

Issue :

13

Database :

Supplemental Index

Journal :

Journal of Medicinal Chemistry

Publication Type :

Academic Journal

Accession number :

108294458

Full Text :

https://doi.org/10.1021/acs.jmedchem.5b00183