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Cervical incompetence prevention randomized cerclage trial: emergency cerclage with bed rest versus bed rest alone.
- Source :
- American Journal of Obstetrics & Gynecology; Oct2003, Vol. 189 Issue 4, p907-910, 4p
- Publication Year :
- 2003
-
Abstract
- <bold>Objective: </bold>The purpose of this study was to compare preterm delivery rates and neonatal morbidity/mortality rates for women with cervical incompetence with membranes at or beyond a dilated external cervical os that was treated with emergency cerclage, bed rest plus indomethacin, versus just bed rest.<bold>Study Design: </bold>Women with cervical incompetence with membranes at or beyond a dilated external cervical os, before 27 weeks of gestation, were treated with antibiotics and bed rest and randomly assigned for emergency cerclage and indomethacin or bed rest only.<bold>Results: </bold>Twenty-three women were included; 13 women were allocated randomly to the emergency cerclage and indomethacin group, and 10 women were allocated randomly to the bed rest-only group. Gestational age at time of randomization was 22.2 weeks in the emergency cerclage and indomethacin group and 23.0 weeks in the bed rest-only group. Mean interval from randomization until delivery was 54 days in the emergency cerclage and indomethacin group and 20 days in the bed rest-only group (P=.046). Mean gestational age at delivery was 29.9 weeks in the emergency cerclage and indomethacin group and 25.9 weeks in the bed rest-only group. Preterm delivery before 34 weeks of gestation was significantly lower in the emergency cerclage and indomethacin group, with 7 of 13 deliveries versus all 10 deliveries in the bed rest-only group (P=.02).<bold>Conclusions: </bold>Emergency cerclage, indomethacin, antibiotics, and bed rest reduce preterm delivery before 34 weeks compared with bed rest and antibiotics alone. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00029378
- Volume :
- 189
- Issue :
- 4
- Database :
- Supplemental Index
- Journal :
- American Journal of Obstetrics & Gynecology
- Publication Type :
- Academic Journal
- Accession number :
- 106772820
- Full Text :
- https://doi.org/10.1067/s0002-9378(03)00718-x