MicroRNA Polymorphisms and Risk of Colorectal Cancer.

The article presents study on the contribution of micro ribonucleic acid (miRNA)-related polymorphisms to the etiology of colorectal cancer across the genome, using the Axiom miRNA Target Site Genotyping Array. It mentions that miRNAs act in post-transcriptional regulation of gene expression and genetic variation in miRNA-encoding sequences may affect the fidelity of the miRNA-mRNA interaction. It adds association of marker and colorectal cancer was examined using logistic regression.