Circulating Biomarkers of Tryptophan and the Kynurenine Pathway and Lung Cancer Risk.

Authors :: Chuang, Shu-Chun
Fanidi, Anouar
Ueland, Per Magne
Relton, Caroline
Midttun, Øivind
Vollset, Stein Emil
Gunter, Marc J.
Seckl, Michael J.
Travis, Ruth C.
Wareham, Nicholas
Trichopoulou, Antonia
Lagiou, Pagona
Trichopoulos, Dimitrios
Peeters, Petra H. M.
Bueno-de-Mesquita, H. Bas
Boeing, Heiner
Wientzek, Angelika
Kuehn, Tilman
Kaaks, Rudolf
Tumino, Rosario
Source :: Cancer Epidemiology, Biomarkers & Prevention; Mar2014, Vol. 23 Issue 3, p461-468, 8p
Publication Year :: 2014
Abstract: The article presents a study revealing the association of biomarkers of tryptophan metabolism with subsequent lung cancer risk. Tables and figures are presented showing the tryptophan degradation pathway and potential implications of 2,3-dioxygenase (IDO) induction, the baseline and clinical characteristics of study participants, and the associations between tryptophan, kynurenine, kynurenine/tryptophan (KTR), and lung cancer risks overall.

Full Text Access

Tools