Uterine sarcomas and parasitic myomas after laparoscopic hysterectomy with power morcellation.

Objective The purpose of this study was to describe the incidence and risk factors for uterine sarcomas and parasitic myomas at the time of power morcellation. Study Design We performed a retrospective review of 3523 women who underwent laparoscopic hysterectomy from 2001-2012. Univariate analyses were used for the morcellation cases to identify potential risk factors. Multivariable logistic regression was performed. Results Nine hundred forty-one patients underwent power morcellation at the time of hysterectomy; 10 of 941 patients (1.1%) were diagnosed subsequently with uterine sarcomas or parasitic myomas. The overall incidence of uterine sarcoma was 6 of 941 (0.6%), with a median age of 47 years (range, 41–52 years). There was no association among any of the factors analyzed and uterine sarcoma. Three of 6 patients had sarcoma diagnosed on initial pathologic evaluation of the morcellated specimen; 3 patients had delayed diagnosis of sarcoma with benign disease at the time of the initial procedure (median time to second evaluation, 6 years). For parasitic myomas (n = 4), the median age was 35 years (range, 32–40 years), and the median time to second evaluation was 5 years. On multivariate analysis, age <40 years (odds ratio, 26; 95% confidence interval, 2.7015–261.9; P ≤ .01) was associated with higher risk of the development of parasitic myomas. Conclusion Uterine sarcoma was found in 0.6% of patients who underwent power morcellation but was not found to be associated significantly with any preoperative factors. All 6 cases were noted to have apparent fibroid tumors as an indication for their hysterectomy. Age <40 years was a risk factor for parasitic myomas after power morcellation. Patients should be counseled about these complications before power morcellation. [ABSTRACT FROM AUTHOR]