The Mut UL5-I682R Marek's Disease Virus with a Single Nucleotide Mutation Within the Helicase-Primase Subunit Gene not only Reduces Virulence but also Provides Partial Vaccinal Protection Against Marek's Disease.

The article discusses the genetic manipulation of Marek's disease virus. It states that altering a gene in the virus leads to reduction in its virulence and when used in conjunction with Turkey Herpesvirus boosts protection against the virus. Topics include recombinant antibodies, in vitro studies, and genome sequencing of the virus.