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Effects of Camellia sinensis L. (green tea) extract on the body and testicular weight changes in adult Wistar rate.

Authors :
Hijazi, Muhammad Mazhar
Khatoon, Nasira
Azmi, Muhammad Arshad
Rajput, Muhammad Tariq
Hussain Zaidi, Syed Ijaz
Azmi, Muhammad Ahmed
Perveen, Rehana
Hassan Naqvi, Syed Naimul
Rashid, Muhammad
Source :
Pakistan Journal of Pharmaceutical Sciences; Jan2015, Vol. 28 Issue 1, p249-253, 5p, 1 Illustration
Publication Year :
2015

Abstract

This research was aimed to study the effects of oral administration of Camellia sinensis L. on the testicular and body weights of adult Wistar rats for short and long time periods. The adult Wistar rats were divided into 3 groups (A, B and C). Every group had ten rats. Green tea extract 0.692% (w/v) was given to groups A and B on daily basis. The extracts were prepared fresh and given for a period of ten and thirty days, respectively, while distilled water was given to the group C rats only. The adult Wistar rats were sacrificed on eleventh and thirty-first day of experiment for the particular groups. The testes were dissected out cautiously, free from the supporter tissues and weighed to the adjacent 1 mg. There is no significant difference in the body weight in all 3 groups. Moreover, it was observed that Wistar rat's testicular weight was considerably increased in group B but no major changes were seen in group A. Our results indicated that green tea when given for short period of time may be effective to the testes but has no consequence on Wistar rat's body weight. However, it is indistinct if these alterations are reversible. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1011601X
Volume :
28
Issue :
1
Database :
Supplemental Index
Journal :
Pakistan Journal of Pharmaceutical Sciences
Publication Type :
Academic Journal
Accession number :
100220117