Microwave-Assisted Pd-Catalyzed Desulfitative C—S Coupling of Arylsulfinate Metal Salts and Alkanethiols.

This paper reports a palladium-catalyzed C-S coupling of arylsulfinate metal salts and alkanethiols via liberation of sulfur dioxide. The use of PdCl2as the catalyst in combination with AgNO3as the oxidant under microwave irradiation results in the synthetically and biologically important aryl alkyl sulfides. A variety of arylsulfinate metal salts, such as sodium, potassium, lithium, silver, zinc, and copper salts, are tolerated well in this reaction. [ABSTRACT FROM AUTHOR]