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Smoking cessation in smokers who smoke menthol and non-menthol cigarettes.
- Source :
- Addiction; Dec2014, Vol. 109 Issue 12, p2107-2117, 11p, 1 Diagram, 6 Charts
- Publication Year :
- 2014
-
Abstract
- Aims To assess the relations of menthol cigarette use with measures of cessation success in a large comparative effectiveness trial ( CET). Design Participants were randomized to one of six medication treatment conditions in a randomized double-blind, placebo-controlled clinical trial. All participants received six individual counseling sessions. Setting Community-based smokers in two communities in Wisconsin, USA. Participants A total of 1504 adult smokers who smoked at least 10 cigarettes per day during the past 6 months and reported being motivated to quit smoking. The analysis sample comprised 1439 participants: 814 white non-menthol smokers, 439 white menthol smokers and 186 African American ( AA) menthol smokers. There were too few AA non-menthol smokers ( n = 16) to be included in the analyses. Interventions Nicotine lozenge, nicotine patch, bupropion sustained release, nicotine patch + nicotine lozenge, bupropion + nicotine lozenge and placebo. Measurements Biochemically confirmed 7-day point-prevalence abstinence assessed at 4, 8 and 26 weeks post-quit. Findings In longitudinal abstinence analyses (generalized estimating equations) controlling for cessation treatment, menthol smoking was associated with reduced likelihood of smoking cessation success relative to non-menthol smoking [model-based estimates of abstinence = 31 versus 38%, respectively; odds ratio ( OR) = 0.71, 95% confidence interval ( CI) = 0.59, 0.86]. In addition, among menthol smokers, AA women were at especially high risk of cessation failure relative to white women (estimated abstinence = 17 versus 35%, respectively; OR = 2.63, 95% CI = 1.75, 3.96; estimated abstinence rates for AA males and white males were both 30%, OR = 1.06, 95% CI = 0.60, 1.66). Conclusion In the United States, smoking menthol cigarettes appears to be associated with reduced cessation success compared with non-menthol smoking, especially in African American females. [ABSTRACT FROM AUTHOR]
- Subjects :
- BUPROPION
BLACK people
CHI-squared test
COMPARATIVE studies
CONFIDENCE intervals
LONGITUDINAL method
HEALTH outcome assessment
QUESTIONNAIRES
RACE
RESEARCH funding
STATISTICAL sampling
SEX distribution
SMOKING cessation
T-test (Statistics)
TOBACCO
WHITE people
SECONDARY analysis
RANDOMIZED controlled trials
TREATMENT effectiveness
BLIND experiment
DATA analysis software
DESCRIPTIVE statistics
NICOTINE replacement therapy
ODDS ratio
THERAPEUTICS
Subjects
Details
- Language :
- English
- ISSN :
- 09652140
- Volume :
- 109
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- Addiction
- Publication Type :
- Academic Journal
- Accession number :
- 99345414
- Full Text :
- https://doi.org/10.1111/add.12661