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Genetic Findings in Obsessive-Compulsive Disorder Connect to Brain-Derived Neutrophic Factor and Mammalian Target of Rapamycin Pathways: Implications for Drug Development.

Authors :
Grados, Marco
Sung, Hyung Mo
Kim, Sejin
Srivastava, Siddharth
Source :
Drug Development Research; Sep2014, Vol. 75 Issue 6, p372-383, 12p
Publication Year :
2014

Abstract

The article presents a review of genetic findings in obsessive-compulsive disorder (OCD). It mentions the use of bioinformatics approaches in locating pathways relevant to neuroprotection. It notes that OCD susceptibility gene products affect cyclic adenosine monophosphate response element (CREB)-binding protein (CBP) and other targets.

Details

Language :
English
ISSN :
02724391
Volume :
75
Issue :
6
Database :
Complementary Index
Journal :
Drug Development Research
Publication Type :
Academic Journal
Accession number :
97903457
Full Text :
https://doi.org/10.1002/ddr.21223