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Sliding filaments and mitotic spindle organization.
- Source :
- Nature Cell Biology; Aug2014, Vol. 16 Issue 8, p737-739, 3p
- Publication Year :
- 2014
-
Abstract
- Mitosis depends upon the action of the mitotic spindle, a subcellular machine that uses microtubules (MTs) and motors to assemble itself and to coordinate chromosome segregation. Recent work illuminates how the motor-driven poleward sliding of MTs - nucleated at centrosomes, chromosomes and on pre-existing MTs - contributes to spindle assembly and length control. [ABSTRACT FROM AUTHOR]
- Subjects :
- MITOSIS
MICROTUBULES
CHROMOSOMES
CENTROSOMES
NUCLEATION
Subjects
Details
- Language :
- English
- ISSN :
- 14657392
- Volume :
- 16
- Issue :
- 8
- Database :
- Complementary Index
- Journal :
- Nature Cell Biology
- Publication Type :
- Academic Journal
- Accession number :
- 97316249
- Full Text :
- https://doi.org/10.1038/ncb3019