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A survey of rare coding variants in candidate genes in schizophrenia by deep sequencing.

Authors :
Hu, X
Zhang, B
Liu, W
Paciga, S
He, W
Lanz, T A
Kleiman, R
Dougherty, B
Hall, S K
McIntosh, A M
Lawrie, S M
Power, A
John, S L
Blackwood, D
St Clair, D
Brandon, N J
Source :
Molecular Psychiatry; Aug2014, Vol. 19 Issue 8, p858-859, 2p
Publication Year :
2014

Abstract

The article presents a survey of the rare coding variants in candidate genes in schizophrenia by deep sequencing. Topics discussed include 525 patients diagnosed of having schizophrenia, coding sequences through the use Nimblegen capture array and Illumina HiSeq paired-end sequencing at the Beijing Genome Institute (BGI) Inc., and damaging missense variants which can contribute schizophrenia etiology.

Details

Language :
English
ISSN :
13594184
Volume :
19
Issue :
8
Database :
Complementary Index
Journal :
Molecular Psychiatry
Publication Type :
Academic Journal
Accession number :
97191344
Full Text :
https://doi.org/10.1038/mp.2013.131